Inflammatory demyelinating polyradiculitis in a patient with acute disseminated encephalomyelitis (ADEM).
Identifieur interne : 000C03 ( Main/Exploration ); précédent : 000C02; suivant : 000C04Inflammatory demyelinating polyradiculitis in a patient with acute disseminated encephalomyelitis (ADEM).
Auteurs : A. Kinoshita [Japon] ; M. Hayashi [Japon] ; K. Miyamoto [Japon] ; M. Oda [Japon] ; H. Tanabe [Japon]Source :
- Journal of Neurology, Neurosurgery & Psychiatry [ 0022-3050 ] ; 1996-01.
English descriptors
- Teeft :
- Active demyelination, Adem, Axon, Brachial plexus, Characteristic feature, Demyelinating, Demyelinating lesions, Demyelinating polyradiculitis, Demyelination, Fasciculus, Fibre, Fulminant case, Great physician, Inflammatory demyelinating polyradiculitis, Lesion, Macrophage, Macrophage infiltration, Marcel proust, Multiple sclerosis, Myelin, Myelin breakdown, Neurological hospital, Neurology, Onion bulb formation, Pathological changes, Pathological findings, Peripheral nerves, Posterior roots, Same fasciculus, Sclerosis, Spinal, Spinal cord, Spinal nerve roots, Spinal roots, Transverse semithin section, White matter.
Abstract
A patient with severe acute disseminated encephalomyelitis died 12 days after the first symptom. Necropsy showed widespread severe demyelination in the CNS and some foci of demyelination in the spinal roots. The lesions in the peripheral nervous system were characterised by myelin stripping and the presence of macrophages, being severest in the spinal nerve roots. Some axons were completely demyelinated, whereas the axons themselves were preserved. Pathologically established ongoing demyelination in both CNS and peripheral nervous systems raises the possibility of a shared pathological epitope.
Url:
DOI: 10.1136/jnnp.60.1.87
Affiliations:
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Miyamoto</name><affiliation wicri:level="4"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Neurology, Faculty of Medicine, Kyoto University</wicri:regionArea><placeName><settlement type="city">Kyoto</settlement><region type="prefecture">Région du Kansai</region></placeName><orgName type="university">Université de Kyoto</orgName></affiliation></author><author><name sortKey="Oda, M" sort="Oda, M" uniqKey="Oda M" first="M" last="Oda">M. Oda</name><affiliation wicri:level="4"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Neurology, Faculty of Medicine, Kyoto University</wicri:regionArea><placeName><settlement type="city">Kyoto</settlement><region type="prefecture">Région du Kansai</region></placeName><orgName type="university">Université de Kyoto</orgName></affiliation></author><author><name sortKey="Tanabe, H" sort="Tanabe, H" uniqKey="Tanabe H" first="H" last="Tanabe">H. Tanabe</name><affiliation wicri:level="4"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Neurology, Faculty of Medicine, Kyoto University</wicri:regionArea><placeName><settlement type="city">Kyoto</settlement><region type="prefecture">Région du Kansai</region></placeName><orgName type="university">Université de Kyoto</orgName></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Neurology, Neurosurgery & Psychiatry</title><title level="j" type="abbrev">J Neurol Neurosurg Psychiatry</title><idno type="ISSN">0022-3050</idno><idno type="eISSN">1468-330X</idno><imprint><publisher>BMJ Publishing Group Ltd</publisher><date type="published" when="1996-01">1996-01</date><biblScope unit="volume">60</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="87">87</biblScope></imprint><idno type="ISSN">0022-3050</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0022-3050</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Active demyelination</term><term>Adem</term><term>Axon</term><term>Brachial plexus</term><term>Characteristic feature</term><term>Demyelinating</term><term>Demyelinating lesions</term><term>Demyelinating polyradiculitis</term><term>Demyelination</term><term>Fasciculus</term><term>Fibre</term><term>Fulminant case</term><term>Great physician</term><term>Inflammatory demyelinating polyradiculitis</term><term>Lesion</term><term>Macrophage</term><term>Macrophage infiltration</term><term>Marcel proust</term><term>Multiple sclerosis</term><term>Myelin</term><term>Myelin breakdown</term><term>Neurological hospital</term><term>Neurology</term><term>Onion bulb formation</term><term>Pathological changes</term><term>Pathological findings</term><term>Peripheral nerves</term><term>Posterior roots</term><term>Same fasciculus</term><term>Sclerosis</term><term>Spinal</term><term>Spinal cord</term><term>Spinal nerve roots</term><term>Spinal roots</term><term>Transverse semithin section</term><term>White matter</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A patient with severe acute disseminated encephalomyelitis died 12 days after the first symptom. Necropsy showed widespread severe demyelination in the CNS and some foci of demyelination in the spinal roots. The lesions in the peripheral nervous system were characterised by myelin stripping and the presence of macrophages, being severest in the spinal nerve roots. Some axons were completely demyelinated, whereas the axons themselves were preserved. Pathologically established ongoing demyelination in both CNS and peripheral nervous systems raises the possibility of a shared pathological epitope.</div></front></TEI><affiliations><list><country><li>Japon</li></country><region><li>Région du Kansai</li></region><settlement><li>Kyoto</li></settlement><orgName><li>Université de Kyoto</li></orgName></list><tree><country name="Japon"><region name="Région du Kansai"><name sortKey="Kinoshita, A" sort="Kinoshita, A" uniqKey="Kinoshita A" first="A" last="Kinoshita">A. Kinoshita</name></region><name sortKey="Hayashi, M" sort="Hayashi, M" uniqKey="Hayashi M" first="M" last="Hayashi">M. Hayashi</name><name sortKey="Miyamoto, K" sort="Miyamoto, K" uniqKey="Miyamoto K" first="K" last="Miyamoto">K. Miyamoto</name><name sortKey="Oda, M" sort="Oda, M" uniqKey="Oda M" first="M" last="Oda">M. Oda</name><name sortKey="Tanabe, H" sort="Tanabe, H" uniqKey="Tanabe H" first="H" last="Tanabe">H. Tanabe</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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